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Astragaloside IV inhibits excessive mesangial cell proliferation and renal fibrosis caused by diabetic nephropathy via modulation of the TGF-β1/Smad/miR-192 signaling pathway

Astragaloside IV (ASI) exhibits a wide variety of pharmacological effects in cardiovascular diseases, hepatitis and kidney disease and due to this, ASI has recently become an attractive research target. The present study aimed to determine the effect of ASI on renal fibrosis and the mechanisms under...

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Опубликовано в: :Exp Ther Med
Главные авторы: Mao, Qian, Chen, Cuicui, Liang, Huankun, Zhong, Shuhai, Cheng, Xinbo, Li, Laiqing
Формат: Artigo
Язык:Inglês
Опубликовано: D.A. Spandidos 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6755437/
https://ncbi.nlm.nih.gov/pubmed/31572545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.7887
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