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Astragaloside Inhibits Hepatic Fibrosis by Modulation of TGF-β1/Smad Signaling Pathway

Activation of HSC is a pivotal step in hepatic fibrosis. In the activation of HSC, the TGF-β1 plays a key role that can promote the occurrence of hepatic fibrosis by combining with Smad proteins. Astragaloside is the main active component extracted from Radix Astragali that has the effect of antioxi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Evid Based Complement Alternat Med
Hauptverfasser: Yuan, Xingxing, Gong, Zhiqiang, Wang, Bingyu, Guo, Xueying, Yang, Lei, Li, Dandan, Zhang, Yali
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952439/
https://ncbi.nlm.nih.gov/pubmed/29853950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3231647
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