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Astragaloside Inhibits Hepatic Fibrosis by Modulation of TGF-β1/Smad Signaling Pathway

Activation of HSC is a pivotal step in hepatic fibrosis. In the activation of HSC, the TGF-β1 plays a key role that can promote the occurrence of hepatic fibrosis by combining with Smad proteins. Astragaloside is the main active component extracted from Radix Astragali that has the effect of antioxi...

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Bibliografske podrobnosti
izdano v:Evid Based Complement Alternat Med
Main Authors: Yuan, Xingxing, Gong, Zhiqiang, Wang, Bingyu, Guo, Xueying, Yang, Lei, Li, Dandan, Zhang, Yali
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952439/
https://ncbi.nlm.nih.gov/pubmed/29853950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3231647
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