Astragaloside Inhibits Hepatic Fibrosis by Modulation of TGF-β1/Smad Signaling Pathway

Activation of HSC is a pivotal step in hepatic fibrosis. In the activation of HSC, the TGF-β1 plays a key role that can promote the occurrence of hepatic fibrosis by combining with Smad proteins. Astragaloside is the main active component extracted from Radix Astragali that has the effect of antioxi...

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Vydáno v:Evid Based Complement Alternat Med
Hlavní autoři: Yuan, Xingxing, Gong, Zhiqiang, Wang, Bingyu, Guo, Xueying, Yang, Lei, Li, Dandan, Zhang, Yali
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952439/
https://ncbi.nlm.nih.gov/pubmed/29853950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3231647
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