Astragaloside Inhibits Hepatic Fibrosis by Modulation of TGF-β1/Smad Signaling Pathway

Activation of HSC is a pivotal step in hepatic fibrosis. In the activation of HSC, the TGF-β1 plays a key role that can promote the occurrence of hepatic fibrosis by combining with Smad proteins. Astragaloside is the main active component extracted from Radix Astragali that has the effect of antioxi...

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Detalhes bibliográficos
Publicado no:Evid Based Complement Alternat Med
Main Authors: Yuan, Xingxing, Gong, Zhiqiang, Wang, Bingyu, Guo, Xueying, Yang, Lei, Li, Dandan, Zhang, Yali
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952439/
https://ncbi.nlm.nih.gov/pubmed/29853950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/3231647
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