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Structural basis for transcription activation by Crl through tethering of σ(S) and RNA polymerase

In bacteria, a primary σ-factor associates with the core RNA polymerase (RNAP) to control most transcription initiation, while alternative σ-factors are used to coordinate expression of additional regulons in response to environmental conditions. Many alternative σ-factors are negatively regulated b...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Cartagena, Alexis Jaramillo, Banta, Amy B., Sathyan, Nikhil, Ross, Wilma, Gourse, Richard L., Campbell, Elizabeth A., Darst, Seth A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754549/
https://ncbi.nlm.nih.gov/pubmed/31484766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1910827116
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