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Selective eradication of human non-small cell lung cancer cells using aptamer-decorated nanoparticles harboring a cytotoxic drug cargo

Targeted cancer therapy is currently the leading modality to enhance treatment selectivity and efficacy, as well as to minimize untoward toxicity to healthy tissues. Herein, we devised and studied nanoparticles (NPs) composed of the biocompatible block-copolymer PEG-PCL entrapping the hydrophobic ch...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Engelberg, Shira, Netzer, Einat, Assaraf, Yehuda G., Livney, Yoav D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754387/
https://ncbi.nlm.nih.gov/pubmed/31541073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1870-0
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