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Selective eradication of human non-small cell lung cancer cells using aptamer-decorated nanoparticles harboring a cytotoxic drug cargo

Targeted cancer therapy is currently the leading modality to enhance treatment selectivity and efficacy, as well as to minimize untoward toxicity to healthy tissues. Herein, we devised and studied nanoparticles (NPs) composed of the biocompatible block-copolymer PEG-PCL entrapping the hydrophobic ch...

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Podrobná bibliografie
Vydáno v:Cell Death Dis
Hlavní autoři: Engelberg, Shira, Netzer, Einat, Assaraf, Yehuda G., Livney, Yoav D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754387/
https://ncbi.nlm.nih.gov/pubmed/31541073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1870-0
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