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Selective eradication of human non-small cell lung cancer cells using aptamer-decorated nanoparticles harboring a cytotoxic drug cargo

Targeted cancer therapy is currently the leading modality to enhance treatment selectivity and efficacy, as well as to minimize untoward toxicity to healthy tissues. Herein, we devised and studied nanoparticles (NPs) composed of the biocompatible block-copolymer PEG-PCL entrapping the hydrophobic ch...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Engelberg, Shira, Netzer, Einat, Assaraf, Yehuda G., Livney, Yoav D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754387/
https://ncbi.nlm.nih.gov/pubmed/31541073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1870-0
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