Gentamicin Affects the Bioenergetics of Isolated Mitochondria and Collapses the Mitochondrial Membrane Potential in Cochlear Sensory Hair Cells

Aminoglycoside antibiotics are widely prescribed to treat a variety of serious bacterial infections. They are extremely useful clinical tools, but have adverse side effects such as oto- and nephrotoxicity. Once inside a cell they are thought to cause mitochondrial dysfunction, subsequently leading t...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: O’Reilly, Molly, Young, Luke, Kirkwood, Nerissa K., Richardson, Guy P., Kros, Corné J., Moore, Anthony L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6753894/
https://ncbi.nlm.nih.gov/pubmed/31572129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00416
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