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Transduction without Tip Links in Cochlear Hair Cells Is Mediated by Ion Channels with Permeation Properties Distinct from Those of the Mechano-Electrical Transducer Channel

Tip links between adjacent stereocilia are believed to gate mechano-electrical transducer (MET) channels and mediate the electrical responses of sensory hair cells. We found that mouse auditory hair cells that lack tip links due to genetic mutations or exposure to the Ca(2+) chelator BAPTA can, howe...

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Detalhes bibliográficos
Main Authors: Marcotti, Walter, Corns, Laura F., Desmonds, Terri, Kirkwood, Nerissa K., Richardson, Guy P., Kros, Corné J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988408/
https://ncbi.nlm.nih.gov/pubmed/24741041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4086-13.2014
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