Transduction without Tip Links in Cochlear Hair Cells Is Mediated by Ion Channels with Permeation Properties Distinct from Those of the Mechano-Electrical Transducer Channel

Tip links between adjacent stereocilia are believed to gate mechano-electrical transducer (MET) channels and mediate the electrical responses of sensory hair cells. We found that mouse auditory hair cells that lack tip links due to genetic mutations or exposure to the Ca(2+) chelator BAPTA can, howe...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Marcotti, Walter, Corns, Laura F., Desmonds, Terri, Kirkwood, Nerissa K., Richardson, Guy P., Kros, Corné J.
التنسيق: Artigo
اللغة:Inglês
منشور في: Society for Neuroscience 2014
الموضوعات:
Articles
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988408/
https://ncbi.nlm.nih.gov/pubmed/24741041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4086-13.2014
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