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The aminoglycoside antibiotic dihydrostreptomycin rapidly enters mouse outer hair cells through the mechano-electrical transducer channels

The most serious side-effect of the widely used aminoglycoside antibiotics is irreversible intracellular damage to the auditory and vestibular hair cells of the inner ear. The mechanism of entry into the hair cells has not been unequivocally resolved. Here we report that extracellular dihydrostrepto...

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Main Authors: Marcotti, Walter, van Netten, Sietse M, Kros, Corné J
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474200/
https://ncbi.nlm.nih.gov/pubmed/15994187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.085951
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