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The aminoglycoside antibiotic dihydrostreptomycin rapidly enters mouse outer hair cells through the mechano-electrical transducer channels

The most serious side-effect of the widely used aminoglycoside antibiotics is irreversible intracellular damage to the auditory and vestibular hair cells of the inner ear. The mechanism of entry into the hair cells has not been unequivocally resolved. Here we report that extracellular dihydrostrepto...

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Detalhes bibliográficos
Main Authors: Marcotti, Walter, van Netten, Sietse M, Kros, Corné J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1474200/
https://ncbi.nlm.nih.gov/pubmed/15994187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.085951
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