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Tmc1 Point Mutation Affects Ca(2+) Sensitivity and Block by Dihydrostreptomycin of the Mechanoelectrical Transducer Current of Mouse Outer Hair Cells

The transduction of sound into electrical signals depends on mechanically sensitive ion channels in the stereociliary bundle. The molecular composition of this mechanoelectrical transducer (MET) channel is not yet known. Transmembrane channel-like protein isoforms 1 (TMC1) and 2 (TMC2) have been pro...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Corns, Laura F., Johnson, Stuart L., Kros, Corné J., Marcotti, Walter
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4710764/
https://ncbi.nlm.nih.gov/pubmed/26758827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2439-15.2016
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