Gene Co-expression Analysis Identifies Histone Deacetylase 5 and 9 Expression in Midbrain Dopamine Neurons and as Regulators of Neurite Growth via Bone Morphogenetic Protein Signaling

Parkinson’s disease is characterized by the intracellular accumulation of α-synuclein which has been linked to early dopaminergic axonal degeneration. Identifying druggable targets that can promote axonal growth in cells overexpressing α-synuclein is important in order to develop strategies for earl...

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Dettagli Bibliografici
Pubblicato in:Front Cell Dev Biol
Autori principali: Mazzocchi, Martina, Wyatt, Sean L., Mercatelli, Daniela, Morari, Michele, Morales-Prieto, Noelia, Collins, Louise M., Sullivan, Aideen M., O’Keeffe, Gerard W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Cell and Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6753186/
https://ncbi.nlm.nih.gov/pubmed/31572723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00191
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