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The role of growth/differentiation factor 5 (GDF5) in the induction and survival of midbrain dopaminergic neurones: relevance to Parkinson's disease treatment

Growth/differentiation factor-5 (GDF5) is a member of the transforming growth factor-β superfamily which has potent effects on dopaminergic neurones in vitro and in vivo. GDF5 is under investigation as a potential therapeutic agent for Parkinson's disease (PD), which is caused by the progressiv...

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Autori principali: Sullivan, Aideen M, O'Keeffe, Gerard W
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1571542/
https://ncbi.nlm.nih.gov/pubmed/16185246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7580.2005.00447.x
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