Measurement of plasma cell-free mitochondrial tumor DNA improves detection of glioblastoma in patient-derived orthotopic xenograft models

The factors responsible for the low detection rate of cell-free tumor DNA (ctDNA) in the plasma of glioblastoma (GB) patients are currently unknown. In this study, we measured circulating nucleic acids in patient-derived orthotopically implanted xenograft (PDOX) models of GB (n=64) and show that tum...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Mair, Richard, Mouliere, Florent, Smith, Christopher G., Chandrananda, Dineika, Gale, Davina, Marass, Francesco, Tsui, Dana W. Y., Massie, Charlie, Wright, Alan, Watts, Colin, Rosenfeld, Nitzan, Brindle, Kevin M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6753020/
https://ncbi.nlm.nih.gov/pubmed/30389699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-0074
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