RIM-BP2 primes synaptic vesicles via recruitment of Munc13-1 at hippocampal mossy fiber synapses

All synapses require fusion-competent vesicles and coordinated Ca(2+)-secretion coupling for neurotransmission, yet functional and anatomical properties are diverse across different synapse types. We show that the presynaptic protein RIM-BP2 has diversified functions in neurotransmitter release at d...

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Pubblicato in:eLife
Autori principali: Brockmann, Marisa M, Maglione, Marta, Willmes, Claudia G, Stumpf, Alexander, Bouazza, Boris A, Velasquez, Laura M, Grauel, M Katharina, Beed, Prateep, Lehmann, Martin, Gimber, Niclas, Schmoranzer, Jan, Sigrist, Stephan J, Rosenmund, Christian, Schmitz, Dietmar
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2019
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6752948/
https://ncbi.nlm.nih.gov/pubmed/31535974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.43243
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