RIM-binding protein 2 regulates release probability by fine-tuning calcium channel localization at murine hippocampal synapses

The tight spatial coupling of synaptic vesicles and voltage-gated Ca(2+) channels (Ca(V)s) ensures efficient action potential-triggered neurotransmitter release from presynaptic active zones (AZs). Rab-interacting molecule-binding proteins (RIM-BPs) interact with Ca(2+) channels and via RIM with oth...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Grauel, M. Katharina, Maglione, Marta, Reddy-Alla, Suneel, Willmes, Claudia G., Brockmann, Marisa M., Trimbuch, Thorsten, Rosenmund, Tanja, Pangalos, Maria, Vardar, Gülçin, Stumpf, Alexander, Walter, Alexander M., Rost, Benjamin R., Eickholt, Britta J., Haucke, Volker, Schmitz, Dietmar, Sigrist, Stephan J., Rosenmund, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068320/
https://ncbi.nlm.nih.gov/pubmed/27671655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605256113
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