Evaluation of hydroxyurea genotoxicity in patients with sickle cell disease

OBJECTIVE: To evaluate the induction of DNA damage in peripheral blood mononuclear cells of patients with sickle cell disease, SS and SC genotypes, treated with hydroxyurea. METHODS: The study subjects were divided into two groups: one group of 22 patients with sickle cell disease, SS and SC genotyp...

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Dettagli Bibliografici
Pubblicato in:Einstein (Sao Paulo)
Autori principali: de Oliveira, Emanuel Almeida Moreira, Boy, Kenia de Assis, Santos, Ana Paula Pinho, Machado, Carla da Silva, Velloso-Rodrigues, Cibele, Gerheim, Pâmela Souza Almeida Silva, Mendonça, Leonardo Meneghin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Instituto Israelita de Ensino e Pesquisa Albert Einstein 2019
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6750882/
https://ncbi.nlm.nih.gov/pubmed/31508660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.31744/einstein_journal/2019AO4742
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