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Mutagenic and Genotoxic Effect of Hydroxyurea

The hydroxyurea, a cytotoxic drug, is the mainly available therapeutical strategy for the treatment of sickle cell disease. This study aimed to evaluate the mutagenic and genotoxic potential of the hydroxyurea through the Salmonella/Microsome assay and micronucleus test in peripheral blood of mice....

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Autors principals: Santos, Jean L., Bosquesi, Priscila L., Almeida, Adélia E., Chin, Chung Man, Varanda, Eliana A.
Format: Artigo
Idioma:Inglês
Publicat: Master Publishing Group 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3614842/
https://ncbi.nlm.nih.gov/pubmed/23675245
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