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Genomic and epigenomic mapping of leptin-responsive neuronal populations involved in body weight regulation

Genome wide association studies (GWAS) in obesity have identified a large number of noncoding loci located near genes expressed in the central nervous system. However, due to the difficulties in isolating and characterizing specific neuronal subpopulations, few obesity-associated SNPs have been func...

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Vydáno v:Nat Metab
Hlavní autoři: Inoue, Fumitaka, Eckalbar, Walter L., Wang, Yi, Murphy, Karl K., Matharu, Navneet, Vaisse, Christian, Ahituv, Nadav
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6750255/
https://ncbi.nlm.nih.gov/pubmed/31535083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42255-019-0051-x
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