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Decoding enhancers using massively parallel reporter assays

Enhancers control the timing, location and expression levels of their target genes. Nucleotide variation in enhancers has been shown to lead to numerous phenotypes, including human disease. While putative enhancer sequences and nucleotide variation within them can now be detected in a rapid manner u...

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Detalhes bibliográficos
Publicado no:Genomics
Main Authors: Inoue, Fumitaka, Ahituv, Nadav
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540663/
https://ncbi.nlm.nih.gov/pubmed/26072433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2015.06.005
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