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Decoding enhancers using massively parallel reporter assays
Enhancers control the timing, location and expression levels of their target genes. Nucleotide variation in enhancers has been shown to lead to numerous phenotypes, including human disease. While putative enhancer sequences and nucleotide variation within them can now be detected in a rapid manner u...
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| Veröffentlicht in: | Genomics |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4540663/ https://ncbi.nlm.nih.gov/pubmed/26072433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2015.06.005 |
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