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Decoding enhancers using massively parallel reporter assays

Enhancers control the timing, location and expression levels of their target genes. Nucleotide variation in enhancers has been shown to lead to numerous phenotypes, including human disease. While putative enhancer sequences and nucleotide variation within them can now be detected in a rapid manner u...

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Bibliografski detalji
Izdano u:Genomics
Glavni autori: Inoue, Fumitaka, Ahituv, Nadav
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540663/
https://ncbi.nlm.nih.gov/pubmed/26072433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygeno.2015.06.005
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