Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients

The heterogeneous nature of inflammatory bowel disease (IBD) presents challenges, particularly when choosing therapy. Activation of the NF-κB transcription factor is a highly regulated, dynamic event in IBD pathogenesis. Using a lentivirus approach, NF-κB-regulated luciferase was expressed in patien...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Papoutsopoulou, Stamatia, Burkitt, Michael D., Bergey, François, England, Hazel, Hough, Rachael, Schmidt, Lorraine, Spiller, David G., White, Michael H. R., Paszek, Pawel, Jackson, Dean A., Martins Dos Santos, Vitor A. P., Sellge, Gernot, Pritchard, D. Mark, Campbell, Barry J., Müller, Werner, Probert, Chris S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6749845/
https://ncbi.nlm.nih.gov/pubmed/31572379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02168
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