Macrophage-Specific NF-κB Activation Dynamics Can Segregate Inflammatory Bowel Disease Patients

The heterogeneous nature of inflammatory bowel disease (IBD) presents challenges, particularly when choosing therapy. Activation of the NF-κB transcription factor is a highly regulated, dynamic event in IBD pathogenesis. Using a lentivirus approach, NF-κB-regulated luciferase was expressed in patien...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Papoutsopoulou, Stamatia, Burkitt, Michael D., Bergey, François, England, Hazel, Hough, Rachael, Schmidt, Lorraine, Spiller, David G., White, Michael H. R., Paszek, Pawel, Jackson, Dean A., Martins Dos Santos, Vitor A. P., Sellge, Gernot, Pritchard, D. Mark, Campbell, Barry J., Müller, Werner, Probert, Chris S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6749845/
https://ncbi.nlm.nih.gov/pubmed/31572379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02168
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