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Quantitative analysis reveals crosstalk mechanisms of heat shock-induced attenuation of NF-κB signaling at the single cell level

Elevated temperature induces the heat shock (HS) response, which modulates cell proliferation, apoptosis, the immune and inflammatory responses. However, specific mechanisms linking the HS response pathways to major cellular signaling systems are not fully understood. Here we used integrated computa...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Kardyńska, Małgorzata, Paszek, Anna, Śmieja, Jarosław, Spiller, David, Widłak, Wiesława, White, Michael R. H., Paszek, Pawel, Kimmel, Marek
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5945226/
https://ncbi.nlm.nih.gov/pubmed/29708974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006130
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