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Identification of New Antifungal Agents Targeting Chitin Synthesis by a Chemical-Genetic Method

Fungal infection is a leading cause of mortality in immunocompromised population; thus, it is urgent to develop new and safe antifungal agents. Different from human cells, fungi have a cell wall, which is composed mainly of polysaccharide glucan and chitin. The unique cell wall structure is an ideal...

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Vydáno v:Molecules
Hlavní autoři: Li, Yan, Sun, Hongmin, Zhu, Xiaohong, Bian, Cong, Wang, Yanchang, Si, Shuyi
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6749524/
https://ncbi.nlm.nih.gov/pubmed/31470665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24173155
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