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Probing the Effects of Pyrimidine Functional Group Switches on Acyclic Fleximer Analogues for Antiviral Activity

Due to their ability to inhibit viral DNA or RNA replication, nucleoside analogues have been used for decades as potent antiviral therapeutics. However, one of the major limitations of nucleoside analogues is the development of antiviral resistance. In that regard, flexible nucleoside analogues know...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Yates, Mary K., Chatterjee, Payel, Flint, Mike, Arefeayne, Yafet, Makuc, Damjan, Plavec, Janez, Spiropoulou, Christina F., Seley-Radtke, Katherine L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6749450/
https://ncbi.nlm.nih.gov/pubmed/31480658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24173184
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