Methoxymethyl (MOM) Group Nitrogen Protection of Pyrimidines Bearing C-6 Acyclic Side-Chains

Novel N-methoxymethylated (MOM) pyrimidine (4−13) and pyrimidine-2,4-diones (15−17) nucleoside mimetics in which an isobutyl side-chain is attached at the C-6 position of the pyrimidine moiety were synthesized. Synthetic methods via O-persilylated or N-anionic uracil derivatives have been evaluated...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Kraljević, Tatjana Gazivoda, Petrović, Martina, Krištafor, Svjetlana, Makuc, Damjan, Plavec, Janez, Ross, Tobias L., Ametamey, Simon M., Raić-Malić, Silvana
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264546/
https://ncbi.nlm.nih.gov/pubmed/21694675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16065113
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