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Pleiotropic requirements for human TDP-43 in the regulation of cell and organelle homeostasis
TDP-43 is an RNA-binding protein that forms cytoplasmic aggregates in multiple neurodegenerative diseases. Although the loss of normal TDP-43 functions likely contributes to disease pathogenesis, the cell biological consequences of human TDP-43 depletion are not well understood. We, therefore, gener...
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| Pubblicato in: | Life Sci Alliance |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Life Science Alliance LLC
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6749094/ https://ncbi.nlm.nih.gov/pubmed/31527135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201900358 |
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