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Tbet Expression in Regulatory T Cells Is Required to Initiate Th1-Mediated Colitis
In normal conditions gut homeostasis is maintained by the suppressive activity of regulatory T cells (Tregs), characterized by the expression of the transcription factor FoxP3. In human inflammatory bowel disease, which is believed to be the consequence of the loss of tolerance toward antigens norma...
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| Publié dans: | Front Immunol |
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| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6749075/ https://ncbi.nlm.nih.gov/pubmed/31572375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02158 |
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