Tbet Expression in Regulatory T Cells Is Required to Initiate Th1-Mediated Colitis

In normal conditions gut homeostasis is maintained by the suppressive activity of regulatory T cells (Tregs), characterized by the expression of the transcription factor FoxP3. In human inflammatory bowel disease, which is believed to be the consequence of the loss of tolerance toward antigens norma...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Immunol
Päätekijät: Di Giovangiulio, Martina, Rizzo, Angelamaria, Franzè, Eleonora, Caprioli, Flavio, Facciotti, Federica, Onali, Sara, Favale, Agnese, Stolfi, Carmine, Fehling, Hans-Joerg, Monteleone, Giovanni, Fantini, Massimo C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2019
Aiheet:
Immunology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6749075/
https://ncbi.nlm.nih.gov/pubmed/31572375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02158
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