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Pharmacological inhibition of Notch signaling regresses pre-established abdominal aortic aneurysm

Abdominal aortic aneurysm (AAA) is characterized by transmural infiltration of myeloid cells at the vascular injury site. Previously, we reported preventive effects of Notch deficiency on the development of AAA by reduction of infiltrating myeloid cells. In this study, we examined if Notch inhibitio...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sharma, Neekun, Dev, Rishabh, Ruiz-Rosado, Juan de Dios, Partida-Sanchez, Santiago, Guerau-de-Arellano, Mireia, Dhakal, Pramod, Kuivaniemi, Helena, Hans, Chetan P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748927/
https://ncbi.nlm.nih.gov/pubmed/31530833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-49682-0
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