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A regression framework to uncover pleiotropy in large-scale electronic health record data
OBJECTIVE: Pleiotropy, where 1 genetic locus affects multiple phenotypes, can offer significant insights in understanding the complex genotype–phenotype relationship. Although individual genotype–phenotype associations have been thoroughly explored, seemingly unrelated phenotypes can be connected ge...
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| Publicado no: | J Am Med Inform Assoc |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6748812/ https://ncbi.nlm.nih.gov/pubmed/31529123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jamia/ocz084 |
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