A regression framework to uncover pleiotropy in large-scale electronic health record data

OBJECTIVE: Pleiotropy, where 1 genetic locus affects multiple phenotypes, can offer significant insights in understanding the complex genotype–phenotype relationship. Although individual genotype–phenotype associations have been thoroughly explored, seemingly unrelated phenotypes can be connected ge...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Am Med Inform Assoc
Hlavní autoři: Li, Ruowang, Duan, Rui, Kember, Rachel L, Rader, Daniel J, Damrauer, Scott M, Moore, Jason H, Chen, Yong
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
Research and Applications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748812/
https://ncbi.nlm.nih.gov/pubmed/31529123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jamia/ocz084
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky