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Microtubules Gate Tau Condensation to Spatially Regulate Microtubule Functions
Tau is an abundant microtubule-associated protein in neurons. Tau aggregation into insoluble fibrils is a hallmark of Alzheimer’s disease and other dementias(1), yet the physiological state of tau molecules within cells remains unclear. Using single molecule imaging, we directly observe that the mic...
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| Publicado no: | Nat Cell Biol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6748660/ https://ncbi.nlm.nih.gov/pubmed/31481790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-019-0375-5 |
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