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Cooperative Accumulation of Dynein-Dynactin at Microtubule Minus-Ends Drives Microtubule Network Reorganization
Cytoplasmic dynein-1 is a minus-end directed motor protein that transports cargo over long distances and organizes the intracellular microtubule (MT) network. How dynein motor activity is harnessed for these diverse functions remains unknown. Here, we have uncovered a mechanism for how processive dy...
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| Vydáno v: | Dev Cell |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6082141/ https://ncbi.nlm.nih.gov/pubmed/29401420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.12.023 |
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