Laddar...
CDR-H3 loop ensemble in solution – conformational selection upon antibody binding
We analyzed pairs of protein-binding, peptide-binding and hapten-binding antibodies crystallized as complex and in the absence of the antigen with and without conformational differences upon binding in the complementarity-determining region (CDR)-H3 loop. Here, we introduce a molecular dynamics-base...
Sparad:
| I publikationen: | MAbs |
|---|---|
| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Taylor & Francis
2019
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6748594/ https://ncbi.nlm.nih.gov/pubmed/31148507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2019.1618676 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|