The mitochondrial retrograde signaling regulates Wnt signaling to promote tumorigenesis in colon cancer

Cancer cells are known to upregulate aerobic glycolysis to promote growth, proliferation, and survival. However, the role of mitochondrial respiration in tumorigenesis remains elusive. Here we report that inhibition of mitochondrial function by silencing TFAM, a key transcription factor essential fo...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Wen, Yang-An, Xiong, Xiaopeng, Scott, Timothy, Li, Austin T., Wang, Chi, Weiss, Heidi L., Tan, Li, Bradford, Emily, Fan, Teresa W. M., Chandel, Navdeep S., Barrett, Terrence A., Gao, Tianyan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748256/
https://ncbi.nlm.nih.gov/pubmed/30659235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0265-6
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