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Molecular basis of dimerization of initiator caspase was revealed by crystal structure of caspase-8 pro-domain
The assembly of death-inducing signaling complex (DISC) for activation of initiator caspase is a key step for the receptor-mediated apoptosis signaling. Many death effector domain (DED)-containing proteins are involved in DISC assembly and controlling. One of the main DISC component, caspase-8, cont...
Gardado en:
| Publicado en: | Cell Death Differ |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6748139/ https://ncbi.nlm.nih.gov/pubmed/30206319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0200-x |
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