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Suppressor of hepatocellular carcinoma RASSF1A activates autophagy initiation and maturation
RASSF1A (Ras association domain family 1 isoform A) is a tumor suppressor and frequently inactivated by promoter hypermethylation in hepatocellular carcinoma (HCC). Autophagy is to degrade misfolded or aggregated proteins and dysfunctional organelles. Autophagy defects enhance oxidative stress and g...
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| Publicado no: | Cell Death Differ |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6748129/ https://ncbi.nlm.nih.gov/pubmed/30315205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0211-7 |
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