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Suppressor of hepatocellular carcinoma RASSF1A activates autophagy initiation and maturation
RASSF1A (Ras association domain family 1 isoform A) is a tumor suppressor and frequently inactivated by promoter hypermethylation in hepatocellular carcinoma (HCC). Autophagy is to degrade misfolded or aggregated proteins and dysfunctional organelles. Autophagy defects enhance oxidative stress and g...
Shranjeno v:
| izdano v: | Cell Death Differ |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group UK
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6748129/ https://ncbi.nlm.nih.gov/pubmed/30315205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0211-7 |
| Oznake: |
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