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Autophagy Inhibitor LRPPRC Suppresses Mitophagy through Interaction with Mitophagy Initiator Parkin

Autophagy plays an important role in tumorigenesis. Mitochondrion-associated protein LRPPRC interacts with MAP1S that interacts with LC3 and bridges autophagy components with microtubules and mitochondria to affect autophagy flux. Dysfunction of LRPPRC and MAP1S is associated with poor survival of o...

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Autori principali: Zou, Jing, Yue, Fei, Li, Wenjiao, Song, Kun, Jiang, Xianhan, Yi, Jinglin, Liu, Leyuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983268/
https://ncbi.nlm.nih.gov/pubmed/24722279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094903
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