Phosphoprotein patterns predict trametinib responsiveness and optimal trametinib sensitisation strategies in melanoma

Malignant melanoma is a highly aggressive form of skin cancer responsible for the majority of skin cancer-related deaths. Recent insight into the heterogeneous nature of melanoma suggests more personalised treatments may be necessary to overcome drug resistance and improve patient care. To this end,...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Rožanc, Jan, Sakellaropoulos, Theodore, Antoranz, Asier, Guttà, Cristiano, Podder, Biswajit, Vetma, Vesna, Rufo, Nicole, Agostinis, Patrizia, Pliaka, Vaia, Sauter, Thomas, Kulms, Dagmar, Rehm, Markus, Alexopoulos, Leonidas G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748097/
https://ncbi.nlm.nih.gov/pubmed/30323272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0210-8
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