Circular RNA circAGO2 drives cancer progression through facilitating HuR-repressed functions of AGO2-miRNA complexes

Argonaute 2 (AGO2), the core component of microRNA (miRNA)-induced silencing complex, plays a compelling role in tumorigenesis and aggressiveness. However, the mechanisms regulating the functions of AGO2 in cancer still remain elusive. Herein, we indentify one intronic circular RNA (circRNA) generat...

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Pubblicato in:Cell Death Differ
Autori principali: Chen, Yajun, Yang, Feng, Fang, Erhu, Xiao, Wenjing, Mei, Hong, Li, Huanhuan, Li, Dan, Song, Huajie, Wang, Jianqun, Hong, Mei, Wang, Xiaojing, Huang, Kai, Zheng, Liduan, Tong, Qiangsong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748083/
https://ncbi.nlm.nih.gov/pubmed/30341421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0220-6
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