Therapeutic targeting of circ‐CUX1/EWSR1/MAZ axis inhibits glycolysis and neuroblastoma progression

Aerobic glycolysis is a hallmark of metabolic reprogramming in tumor progression. However, the mechanisms regulating glycolytic gene expression remain elusive in neuroblastoma (NB), the most common extracranial malignancy in childhood. Herein, we identify that CUT‐like homeobox 1 (CUX1) and CUX1‐gen...

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Udgivet i:EMBO Mol Med
Main Authors: Li, Huanhuan, Yang, Feng, Hu, Anpei, Wang, Xiaojing, Fang, Erhu, Chen, Yajun, Li, Dan, Song, Huajie, Wang, Jianqun, Guo, Yanhua, Liu, Yang, Li, Hongjun, Huang, Kai, Zheng, Liduan, Tong, Qiangsong
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6895612/
https://ncbi.nlm.nih.gov/pubmed/31709724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201910835
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