The bromodomain protein BRD4 positively regulates necroptosis via modulating MLKL expression

Necroptosis is a programmed form of necrotic cell death, which is tightly regulated by the necroptotic signaling pathway containing receptor-interacting protein (RIP)1, RIP3, and mixed-lineage kinase domain-like (MLKL) protein. In addition to the RIP1-RIP3-MLKL axis, other factors regulating necropt...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Xiong, Yu, Li, Linli, Zhang, Liting, Cui, Yangyang, Wu, Chengyong, Li, Hui, Chen, Kai, Yang, Qiuyuan, Xiang, Rong, Hu, Yiguo, Huang, Shile, Wei, Yuquan, Yang, Shengyong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748082/
https://ncbi.nlm.nih.gov/pubmed/30644439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-018-0262-9
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