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Measuring Signaling and RNA-Seq in the Same Cell Links Gene Expression to Dynamic Patterns of NF-κB Activation

Signaling proteins display remarkable cell-to-cell heterogeneity in their dynamic responses to stimuli, but the consequences of this heterogeneity remain largely unknown. For instance, the contribution of the dynamics of the innate immune transcription factor nuclear factor κB (NF-κB) to gene expres...

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Detalhes bibliográficos
Publicado no:Cell Syst
Main Authors: Lane, Keara, Valen, David Van, DeFelice, Mialy M., Macklin, Derek N., Kudo, Takamasa, Jaimovich, Ariel, Carr, Ambrose, Meyer, Tobias, Pe’er, Dana, Boutet, Stéphane C., Covert, Markus W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6748049/
https://ncbi.nlm.nih.gov/pubmed/28396000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.03.010
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