Intermedin in Paraventricular Nucleus Attenuates Ang II-Induced Sympathoexcitation through the Inhibition of NADPH Oxidase-Dependent ROS Generation in Obese Rats with Hypertension

Increased reactive oxygen species (ROS) induced by angiotensin II (Ang II) in the paraventricular nucleus (PVN) play a critical role in sympathetic overdrive in hypertension (OH). Intermedin (IMD), a bioactive peptide, has extensive clinically prospects in preventing and treating cardiovascular dise...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kang, Ying, Ding, Lei, Dai, Hangbing, Wang, Fangzheng, Zhou, Hong, Gao, Qing, Xiong, Xiaoqing, Zhang, Feng, Song, Tianrun, Yuan, Yan, Zhu, Guoqing, Zhou, Yebo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747263/
https://ncbi.nlm.nih.gov/pubmed/31466304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20174217
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