Sympathoexcitation in ANG II-salt hypertension involves reduced SK channel function in the hypothalamic paraventricular nucleus

Hypertension (HTN) resulting from subcutaneous infusion of ANG II and dietary high salt (HS) intake involves sympathoexcitation. Recently, we reported reduced small-conductance Ca(2+)-activated K(+) (SK) current and increased excitability of presympathetic neurons in the paraventricular nucleus (PVN...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Larson, Robert A., Gui, Le, Huber, Michael J., Chapp, Andrew D., Zhu, Jianhua, LaGrange, Lila P., Shan, Zhiying, Chen, Qing-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Cardiovascular Neurohormonal Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4469880/
https://ncbi.nlm.nih.gov/pubmed/25862832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00832.2014
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