Investigating the Role of VDR and Megalin in Semi-Selectivity of Side-Chain Modified 19-nor Analogs of Vitamin D

1,25-dihydroxyvitamin D(3) (1,25D3) is implicated in many cellular functions, including cell proliferation and differentiation, thus exerting potential antitumor effects. A major limitation for therapeutic use of 1,25D3 are potent calcemic activities. Therefore, synthetic analogs of 1,25D3 for use i...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Int J Mol Sci
Hlavní autoři: Berkowska, Klaudia, Corcoran, Aoife, Grudzień, Małgorzata, Jakuszak, Agnieszka, Chodyński, Michał, Kutner, Andrzej, Marcinkowska, Ewa
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6747128/
https://ncbi.nlm.nih.gov/pubmed/31455010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20174183
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky