Investigating the Role of Methylation in Silencing of VDR Gene Expression in Normal Cells during Hematopoiesis and in Their Leukemic Counterparts

(1) Background: Vitamin D receptor (VDR) is present in multiple types of blood cells, and its ligand, 1,25-dihydroxyvitamin D (1,25D), is important for the proper functioning of the immune system. Activity of VDR is higher in hematopoietic stem and progenitor cells than in fully differentiated blood...

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Veröffentlicht in:Cells
Hauptverfasser: Nowak, Urszula, Janik, Sylwia, Marchwicka, Aleksandra, Łaszkiewicz, Agnieszka, Jakuszak, Agnieszka, Cebrat, Małgorzata, Marcinkowska, Ewa
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563846/
https://ncbi.nlm.nih.gov/pubmed/32872475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9091991
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